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510-540 / 1000+ resultsresearch The Malignant Capacity of Skin Tumors Induced by Expression of a Mutant H-Ras Transgene Depends on the Cell Type Targeted
The risk of skin tumors becoming malignant depends on the specific skin cell type affected.
research Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle
miR-31 regulates hair growth by controlling gene expression in hair follicles.
![2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation](/images/research/c3ab0493-64da-4cf6-a867-ccb6b6dca081/small/36924.jpg)
research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation
TCDD speeds up skin barrier formation by increasing certain gene expressions.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
![Genetic Interplays Between Msx2 And Foxn1 Are Required For Notch1 Expression And Hair Shaft Differentiation](/images/research/bf7038ca-20bf-4fb9-8d9a-a11ba432fe33/small/19932.jpg)
research Genetic Interplays Between Msx2 And Foxn1 Are Required For Notch1 Expression And Hair Shaft Differentiation
Msx2 and Foxn1 are both crucial for hair growth and health.
![The Hairless Gene of the Mouse: Relationship of Phenotypic Effects with Expression Profile and Genotype](/images/research/e36101d0-9c14-4466-8605-d02429f1e1f3/small/20047.jpg)
research The Hairless Gene of the Mouse: Relationship of Phenotypic Effects with Expression Profile and Genotype
Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
![Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures](/images/research/d2468eff-1542-47b7-99ba-9d22c88e9fbb/small/20911.jpg)
research Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures
A blood pressure drug, diltiazem, may also help treat influenza.
![Impact of Metformin and Rosiglitazone Treatment on Glucose Transporter 4 mRNA Expression in Women with Polycystic Ovary Syndrome](/images/research/14b0062a-fcfb-4de9-be0e-38666119df01/small/15024.jpg)
research Impact of Metformin and Rosiglitazone Treatment on Glucose Transporter 4 mRNA Expression in Women with Polycystic Ovary Syndrome
Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
![Thyrotropin-Releasing Hormone and Estrogen Differentially Regulate Prolactin and Prolactin Receptor Expression in Female Human Skin and Hair Follicles In Vitro](/images/research/e692e573-726d-408f-a9ef-b2cd353cd231/small/26270.jpg)
research Thyrotropin-Releasing Hormone and Estrogen Differentially Regulate Prolactin and Prolactin Receptor Expression in Female Human Skin and Hair Follicles In Vitro
Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.
![Correlation of Vitamin D and Vitamin D Receptor Expression in Patients with Alopecia Areata: A Clinical Paradigm](/images/research/e06dc52f-3e1e-4a82-9d5e-fbb0cd2d3590/small/18082.jpg)
research Correlation of Vitamin D and Vitamin D Receptor Expression in Patients with Alopecia Areata: A Clinical Paradigm
People with alopecia areata often have lower vitamin D levels, which are linked to more severe and longer-lasting hair loss, but vitamin D receptor levels in the skin don't show the same pattern and don't predict treatment success.
![Exercise Activates the PI3K-AKT Signal Pathway by Decreasing the Expression of 5α-Reductase Type 1 in PCOS Rats](/images/research/d1268386-6328-4ed5-af2d-e4a860bbc856/small/33120.jpg)
research Exercise Activates the PI3K-AKT Signal Pathway by Decreasing the Expression of 5α-Reductase Type 1 in PCOS Rats
Exercise improves insulin sensitivity and hormone regulation in PCOS rats.
![High Auxin and High Phosphate Impact on RSL2 Expression and ROS Homeostasis Linked to Root Hair Growth in Arabidopsis Thaliana](/images/research/d34b345e-8fdc-4bb1-aaac-e1e359903c9a/small/22977.jpg)
research High Auxin and High Phosphate Impact on RSL2 Expression and ROS Homeostasis Linked to Root Hair Growth in Arabidopsis Thaliana
High levels of auxin increase root hair growth by activating RSL2 and producing ROS, while high phosphate levels hinder growth by repressing RSL2.
![Arctiin Blocks Hydrogen Peroxide-Induced Senescence and Cell Death Through MicroRNA Expression Changes in Human Dermal Papilla Cells](/images/research/b569c3d9-3b49-4d8a-9aea-c0f198159e12/small/18781.jpg)
research Arctiin Blocks Hydrogen Peroxide-Induced Senescence and Cell Death Through MicroRNA Expression Changes in Human Dermal Papilla Cells
Arctiin helps protect hair cells from damage and death caused by oxidative stress.
![Cloning, Expression, and Characterization of Rhesus Macaque Types 1 and 2 5alpha-Reductase: Evidence for Mechanism-Based Inhibition by Finasteride](/images/research/77733181-73df-4d13-8ba3-6b71c79dac4e/small/2197.jpg)
research Cloning, Expression, and Characterization of Rhesus Macaque Types 1 and 2 5alpha-Reductase: Evidence for Mechanism-Based Inhibition by Finasteride
Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
research Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly
Loss of Msx2 function causes eye development issues similar to Peters anomaly.
![Tsukushi Is Involved in Wound Healing by Regulating the Expression of Cytokines and Growth Factors](/images/research/cf8f22f8-ca2f-4050-9102-d7b31b91a9dc/small/26304.jpg)
research Tsukushi Is Involved in Wound Healing by Regulating the Expression of Cytokines and Growth Factors
Tsukushi helps control inflammation and aids in wound healing.
research Potential Relationship Between the Canonical Wnt Signaling Pathway and Expression of the Vitamin D Receptor in Alopecia
Targeting the Wnt pathway might help treat hair loss.
research Alopecia Areata Susceptibility Variant in MHC Region Impacts Expressions of Genes Contributing to Hair Keratinization and Is Involved in Hair Loss
A gene variant increases the risk of a type of hair loss by affecting hair protein production.
research HOXC8 Initiates an Ectopic Mammary Program by Regulating FGF10 and TBX3 Expression, and Wnt/β-Catenin Signaling
Hoxc8 gene helps start mammary gland development by controlling specific signals.
![Study on the Zona Pellucida 4 (ZP4) Gene Sequence and Its Expression in the Ovaries of Patients with Polycystic Ovary Syndrome](/images/research/87098d4d-1ca9-4a8a-9cf3-f0ef80dd8792/small/14247.jpg)
research Study on the Zona Pellucida 4 (ZP4) Gene Sequence and Its Expression in the Ovaries of Patients with Polycystic Ovary Syndrome
The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.
![Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells](/images/research/864fc5d4-1702-4876-83a5-3e91eb7a0512/small/35790.jpg)
research Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells
A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
![Neonatal Finasteride Administration Alters Hippocampal α4 and δ GABAAR Subunits Expression and Behavioral Responses to Progesterone in Adult Rats](/images/research/b2b9e8eb-f8a1-4776-ac9a-2a36f54c4682/small/3412.jpg)
research Neonatal Finasteride Administration Alters Hippocampal α4 and δ GABAAR Subunits Expression and Behavioral Responses to Progesterone in Adult Rats
![Effect of Ficus Carica Leaf Extract on the Gene Expression of Selected Factors in HaCaT Cells](/images/research/be245faa-769f-4cf5-b192-0e12df9851ad/small/18272.jpg)
research Effect of Ficus Carica Leaf Extract on the Gene Expression of Selected Factors in HaCaT Cells
Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
![Hair Follicle Development and Related Gene and Protein Expression in Rex Rabbits During the First 8 Weeks of Life](/images/research/f83012bf-5be5-4527-89b4-ec67dfbd6710/small/41183.jpg)
research Hair Follicle Development and Related Gene and Protein Expression in Rex Rabbits During the First 8 Weeks of Life
Rex rabbits' hair follicles develop dynamically in the first 8 weeks, with key genes and proteins changing over time.
![Hominis Placenta Facilitates Hair Regrowth by Upregulating Cellular Proliferation and Expression of Fibroblast Growth Factor-7](/images/research/ce867573-aa40-486c-b657-97a100eb6157/small/14110.jpg)
research Hominis Placenta Facilitates Hair Regrowth by Upregulating Cellular Proliferation and Expression of Fibroblast Growth Factor-7
Hominis Placenta helps hair grow back by increasing cell growth and a specific growth factor.
![L-Ascorbic Acid 2-Phosphate Represses Dihydrotestosterone-Induced Dickkopf-1 Expression in Human Balding Dermal Papilla Cells](/images/research/18d492e9-5fd6-4ccb-8445-8b41b30dee2a/small/26231.jpg)
research L-Ascorbic Acid 2-Phosphate Represses Dihydrotestosterone-Induced Dickkopf-1 Expression in Human Balding Dermal Papilla Cells
Vitamin C derivative reduces hair loss-related protein in cells.
research Ginkgolide B and Bilobalide Promote Growth and Increase β-Catenin Expression in Hair Follicle Dermal Papilla Cells of American Minks
Ginkgolide B and bilobalide help mink hair grow by making skin cells healthier and boosting a key growth protein.
![The Effect of Night Shift Work on the Expression of Clock Genes in Beard Hair Follicle Cells](/images/research/7a0877e9-a104-4e76-b9ab-9019a7654505/small/34870.jpg)
research The Effect of Night Shift Work on the Expression of Clock Genes in Beard Hair Follicle Cells
Night shift work disrupts the body's natural clock genes.
![Generation of Trichogenic Adipose-Derived Stem Cells by Expression of Three Factors](/images/research/ed4f4083-7b54-4dd4-aad7-5fc9ebac5a1b/small/19407.jpg)
research Generation of Trichogenic Adipose-Derived Stem Cells by Expression of Three Factors
Scientists made stem cells that can grow hair by adding three specific factors to them.