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Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

Hair follicles are valuable for regenerative medicine and wound healing.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

JAK inhibitors may soon be a safe and effective treatment for alopecia areata.

Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.

Hair follicle regeneration may slow tumor growth.

Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.

Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.

3D cell-derived matrices improve tissue regeneration and disease modeling.

Overexpressing Tβ4 in goats' hair follicles increases cashmere production and hair follicle growth.

New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.