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    Research 961–990 of 1000+

    1. Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities Signal Transduction and Targeted Therapy · 2022 · 318 citations
    2. Spermidine/spermine-<i>N</i><sup>1</sup>-acetyltransferase: a key metabolic regulator AJP Endocrinology and Metabolism · 2008 · 305 citations
    3. Defective trophoblast function in mice with a targeted mutation of Ets2 Genes & Development · 1998 · 301 citations
    4. Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases Cell · 2020 · 227 citations
    5. Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation The Journal of Cell Biology · 2001 · 195 citations
    6. On the effects of testosterone on brain behavioral functions Frontiers in Neuroscience · 2015 · 186 citations
    7. Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation Proceedings of the National Academy of Sciences · 2013 · 176 citations
    8. Drug Repositioning: New Approaches and Future Prospects for Life-Debilitating Diseases and the COVID-19 Pandemic Outbreak Viruses · 2020 · 170 citations
    9. Quiescent Tissue Stem Cells Evade Immune Surveillance Immunity · 2018 · 169 citations
    10. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012 · 158 citations
    11. Expression of Hypothalamic–Pituitary–Thyroid Axis RelatedGenes in the Human Skin Journal of Investigative Dermatology · 2002 · 155 citations
    12. LPA-producing enzyme PA-PLA<sub>1</sub>α regulates hair follicle development by modulating EGFR signalling The EMBO Journal · 2011 · 151 citations
    13. Estrogen and androgen signaling in the pathogenesis of BPH Nature reviews. Urology · 2011 · 149 citations
    14. Atrichia Caused by Mutations in the Vitamin D Receptor Gene is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene 2001 · 139 citations
    15. FGF5 is a crucial regulator of hair length in humans Proceedings of the National Academy of Sciences of the United States of America · 2014 · 136 citations
    16. Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism PLoS Medicine · 2006 · 135 citations
    17. Dlx3 is a crucial regulator of hair follicle differentiation and cycling Development · 2008 · 132 citations
    18. Evidence for Novel Functions of the Keratin Tail Emerging from a Mutation Causing Ichthyosis Hystrix Journal of Investigative Dermatology · 2001 · 130 citations
    19. Frizzled Receptors in Development and Disease 2016 · 114 citations
    20. Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing Journal of Investigative Dermatology · 2008 · 99 citations
    21. An Autosomal Recessive Form of Monilethrix Is Caused by Mutations in DSG4: Clinical Overlap with Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2006 · 97 citations
    22. WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation Nature Communications · 2017 · 96 citations
    23. K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) Represent the Type I Inner Root Sheath Keratins of the Human Hair Follicle Journal of Investigative Dermatology · 2006 · 93 citations
    24. Inducible deletion of epidermal <i>Dicer</i> and <i>Drosha</i> reveals multiple functions for miRNAs in postnatal skin Development · 2012 · 82 citations
    25. Diseases associated with hidranitis suppurativa: part 2 of a series on hidradenitis Dermatology Online Journal · 2013 · 78 citations
    26. A Missense Mutation within the Helix Initiation Motif of the Keratin K71 Gene Underlies Autosomal Dominant Woolly Hair/Hypotrichosis Journal of Investigative Dermatology · 2012 · 78 citations
    27. SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells Stem Cell Reports · 2017 · 77 citations
    28. Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats Journal of Heredity · 2007 · 75 citations
    29. Genomic Organization, Transcriptomic Analysis, and Functional Characterization of Avian α- and β-Keratins in Diverse Feather Forms Genome Biology and Evolution · 2014 · 72 citations
    30. Expression of Desmoglein 1 Compensates for Genetic Loss of Desmoglein 3 in Keratinocyte Adhesion Journal of Investigative Dermatology · 2002 · 72 citations