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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Some medications might contribute to male infertility, with finasteride showing a high number of reports.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Hair transplants help transgender patients look more like their gender identity, with different procedures for trans women and men.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Finasteride effectively treats hair loss in transgender men with few side effects.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

No definitive link between finasteride and male breast cancer, but further research is needed.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Hair transplantation techniques have improved over time, leading to natural-looking results and high graft survival rates, making it a popular treatment for hair loss.

Hair restoration surgery techniques can effectively treat scalp deformities and have evolved to provide natural-looking results.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Finasteride effectively treats central serous chorioretinopathy.

Finasteride may cause kidney damage.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.

The document concludes that personalized treatment, including lifestyle changes and medication, is essential for managing PCOS in teenagers, while also addressing their psychological well-being.

A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The method effectively detects banned substances in urine for sports antidoping.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Men with Kennedy disease have less chance of hair loss.