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The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

Telogen effluvium is a common hair loss condition where many hairs enter the resting phase, often not noticeable until significant loss occurs, and treatment focuses on the underlying cause.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Adrenal disorders can cause lasting brain and behavior issues in children.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

New treatments for PCOS focus on managing symptoms and improving fertility.

Hyaluronic acid filler injections are a favored non-surgical method to improve facial aging signs due to their convenience, effectiveness, and durability.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.

New treatments for skin diseases are more effective and patient-friendly, but many still lack a cure.

Fzd2 is important for skin and hair development through various signaling ways.

A new lotion with halobetasol and tazarotene successfully treats acne keloidalis nuchae.

Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.

Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.

Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.

Topical tofacitinib is effective in promoting hair growth for non-scarring alopecia.

Good nutrition and vitamins are important for healthy skin and can prevent diseases.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.