research 5α-Reduced Glucocorticoids: A Story of Natural Selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
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research Cicatricial (Scarring) Alopecias: Comprehensive Review and Management
Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
research Update on the Dermatologic Use of Systemic Glucocorticosteroids
Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.
research Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility
Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
research Contribution of the Hair Follicular Pathway to Total Skin Permeation of Topically Applied and Exposed Chemicals
The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.
research Anabolic-Androgenic Steroids and Cardiovascular Risk
Using steroids can increase the risk of heart problems.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Understanding and Addressing Hair Disorders in Transgender Individuals
Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research The Biological Effects of a Pulsed Electrostatic Field with Specific Reference to Hair Electrotrichogenesis
A pulsed electrical field safely and effectively increased hair growth.
research In Vitro and In Vivo Structure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring
Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
research Review of Aseptic Neutrophilic Dermatoses
The review says skin conditions with sterile pustules need more research for better treatments.
research Branching of Spiral Ganglion Neurites Induced by Focal Application of Fibroblast Growth Factor-1
FGF-1 causes spiral ganglion neurites to branch more.
research Development and Evaluation of Antisense shRNA-Encoding Plasmid Loaded Solid Lipid Nanoparticles Against 5-Alpha Reductase Activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
research Hirsutism
Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
research Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes
Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.
research Nonanal Stimulates Growth Factors via Cyclic Adenosine Monophosphate (cAMP) Signaling in Human Hair Follicle Dermal Papilla Cells
Nonanal from fruits and vegetables promotes hair growth by increasing growth factors.
research The Role of Cytochrome P-450 in Dermatology
Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
research Adverse Effects of Sports Supplements in Men
Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.
research The Association Between Exercise and Androgenetic Alopecia: A Survey-Based Study
More exercise might link to hair loss, but other factors also matter.
research A Case of Hyperpigmentation and Acanthosis Nigricans by Testosterone Injections
Testosterone injections can cause skin darkening and thickening.
research The Use of Biodegradable Microneedle Patches to Increase Penetration of Topical Steroid for Prurigo Nodularis
Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.
research Is There a Rationale for the Use of Botulinum Toxin in the Treatment of Androgenetic Alopecia?
Botulinum toxin may help hair loss by increasing blood flow and reducing harmful factors.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Hair Growth-Promoting Effect of Recombinant Human Sonic Hedgehog Proteins
Sonic hedgehog proteins may help grow hair.
research Cutaneous Malignant Melanoma Incidences Analyzed Worldwide by Skin Type Over Advancing Age of Males and Females: Evidence Estrogen and Androgenic Hair Are Risk Factors
Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.
research Synthesis of Novel Iron Nanoparticles Using the Aqueous Extract of the Pumpkin Plant and Their Use in the Treatment of Burns
Iron nanoparticles made from pumpkin extract effectively treated burns and promoted healing in mice.
research Alternative Medicine for Hair Loss
Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.
research Melasma in Men
Treating melasma in men is difficult, especially for the deeper skin layers, and may need more than just topical treatments.
research Endocrine Disorders and Infertility
Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.