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The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.

The study found that family history, personal history of adolescent acne, no pregnancies, hirsutism, office work, stress, and low intake of fruits/vegetables and fish are risk factors for adult female acne.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Melatonin improved mental health and metabolism in women with PCOS.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Hormonal therapies are safe and effective for treating adult women's acne.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Melatonin may help treat PCOS symptoms in rats.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

Hair microRNAs could be effective biomarkers for diagnosing scleroderma.

About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.

Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Dermoscopy is useful for diagnosing various skin, hair, and nail disorders and can reduce the need for biopsies.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.