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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Researchers created human hair follicles using a new method that could help treat hair loss.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.