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Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Successful hair transplant surgery depends on careful patient selection, proper surgical plan and technique, and attentive aftercare.

Dr. Michael Beehner recommends a personalized, careful approach to hairline design in hair replacement surgery for a natural look.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Propranolol affects heart rate and renin levels in minoxidil-treated patients.

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

The PCOS-specific questionnaire needs more work to fully measure quality of life in clinical trials.

The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.

Lovastatin doesn't improve lower urinary tract symptoms treatment.

Tofacitinib and oral minoxidil together effectively regrow hair in severe alopecia areata patients.

BMI is not a significant predictor of complications after gender-affirming penile inversion vaginoplasty.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Llamas often have skin issues like mange, bacterial infections, and allergies, with some treatable by zinc.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

The robotic hair restoration device had a high success rate and was faster than manual methods for Korean patients.

Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.

The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.

The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

The conclusion is that primary scarring alopecia is a complex condition that requires early and accurate diagnosis for effective treatment.

The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.