In this study, adolescents with depressive symptoms were found to have higher urinary excretion rates of certain steroid metabolites, including corticosterone and adrenal hormones, and a specific metabolite ratio was identified as a potential biomarker for distinguishing these patients from healthy controls.
1 citations
,
December 2019 This documentation reviews the absorption, metabolism, and excretion of selenium and its compounds, highlighting the complex interactions and health implications, but reports no new clinical results.
30 citations
,
December 1972 in “Archives of dermatology” This report examines efforts to enhance the efficacy of topical steroids for alopecia areata using penetration-enhancing vehicles and exceptionally high concentrations, noting systemic steroids often lead to relapses and toxicity.
6 citations
,
July 2023 in “Cureus” This study observed a high prevalence of post-COVID-19 symptoms, including exertional dyspnea, cough, fatigue, and myalgia, among patients attending a post-COVID clinic in Southern India, with no significant symptom differences based on hospitalization during acute COVID-19.
31 citations
,
August 1975 in “Journal of Pharmaceutical Sciences” This study found that different species metabolized minoxidil into various products, with monkeys and humans showing similar profiles primarily excreting a glucuronide conjugate, while rats and dogs showed distinct differences.
24 citations
,
April 2008 in “Fertility and sterility” In this study, pioglitazone treatment in insulin-resistant PCOS patients decreased relative 5alpha-reductase activity without significantly affecting cortisol levels or urinary cortisol excretion.
5 citations
,
May 2023 in “Science of the total environment” This study observed that higher PFAS concentrations during adolescence were linked to later pubertal development and lower estradiol levels in females, but not in males, potentially due to PFAS excretion with menstrual fluid.
5 citations
,
January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” This study found that treatment with cyproterone acetate and ethinylestradiol in hirsute women reduced testosterone and androstenedione levels, decreased hair growth, and increased cortisol levels without changing catecholamine excretion.
5 citations
,
January 1976 in “Journal of Endocrinology” This study compared hormone levels between oriental and Caucasian men, finding that while oriental men share similar plasma testosterone levels, their 17-oxosteroid excretion is lower, which may influence beard growth differences.
December 2018 in “Progress in Medical Sciences” This study observed that methanol extract of Phoenix dactilifera improved kidney function in rats at 4 and 8 mg/kg doses, but a 16 mg/kg dose may impair kidney function by affecting urea and potassium excretion.
17 citations
,
January 2022 in “Emerging infectious diseases” This study found that compared to influenza patients, COVID-19 patients had fewer complications overall, but exceptions with higher risks were seen in hair loss, heart failure, mood disorder, and dementia.
14 citations
,
January 1977 in “PubMed” This study found that a specific variant in hair keratin was present mainly in Caucasian samples, with few exceptions showing likely Caucasian admixture.
8 citations
,
February 1997 in “International journal of environmental analytical chemistry” This study determined that most elemental concentrations in Mexican medicinal plants were similar to agricultural products, with bromine being an exception.
2 citations
,
July 2025 in “Scientific Reports” This study identified a novel Acinetobacter species, strain A1-4-2, with exceptional biodegradation abilities and low antibiotic resistance, found in diverse environments and potentially useful for ecological restoration by degrading organic pollutants.
7 citations
,
May 2023 in “Animals” This study observed that Fraser’s dolphins exhibit remarkable skin healing abilities, with type I collagen prevalent in normal skin and type III collagen emerging during early wound healing before returning to normal configuration, suggesting insights for human clinical wound management.
3 citations
,
January 2024 in “Materials advances” This article reviews the properties of cellulose nanocrystals for sustainable development but presents no new experimental results.
6 citations
,
April 2019 in “Pesquisa Veterinária Brasileira” This article reviews the potential risks of various phytotoxins in milk for animals and humans, discussing the need for awareness and further research but providing no new findings.
1 citations
,
September 2017 in “Elsevier eBooks” Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.
August 2019 in “Journal of Investigative Dermatology” This study found that tight junctions extend to the most superficial layer of the stratum granulosum in human skin, challenging previous claims of their limited presence in the epidermis.
48 citations
,
July 1996 in “Human & Experimental Toxicology” Human enzymes can detoxify harmful substances but might also increase their cancer risk.
43 citations
,
October 1955 in “The journal of nutrition/The Journal of nutrition” This study found that male germ-free rats fed semisynthetic diets do not grow as rapidly as their conventional counterparts and require dietary biotin for normal metabolism and folic acid biosynthesis.
27 citations
,
May 1976 in “PubMed” This study concluded that wedge resection in patients with polycystic ovary syndrome did not significantly affect androgen status or the biochemical features of the condition, though most regained regular menstrual cycles and some became pregnant.
7 citations
,
August 2023 in “Life” This review discusses using extracellular vesicles as less invasive surrogates for assessing drug-metabolizing enzymes and transporters, suggesting potential advancements in precision therapy, but reports no new clinical results.
5 citations
,
January 2003 in “Oilseeds and fats, crops and lipids/OCL. Oilseeds & fats crops and lipids” This review discusses the effects of dietary protein and its components on cholesterol, essential fatty acids, and possible health consequences, but presents no new clinical findings.
2 citations
,
January 2009 in “Journal of Oleo Science” In this study, while young rats fed a commercial standard diet with possibly deteriorated oil showed normal growth, they also exhibited liver surface changes and altered serum lipid levels compared to those on a defined diet.
1 citations
,
August 2013 in “International Conference on Alcohol, Drugs and Traffic Safety (T2013), 20th, 2013, Brisbane, Queensland, Australia” This study reported that patients with decreased kidney function had significantly higher levels of ethyl glucuronide in hair compared to healthy volunteers, suggesting caution when using hair EtG levels to assess driving qualifications.
March 2013 in “International Society of Hair Restoration Surgery” Biotin may not effectively promote hair growth.
December 2010 in “Journal of the American Geriatrics Society” This article highlights the complexity of diagnosing hyponatremia in older adults, emphasizing the need to evaluate urinary tract obstruction, medication effects, and age-related changes rather than relying solely on spot urinary values.
February 1990 in “Pathology, research and practice” This study in rats with a portocaval shunt observed severe ultrastructural damage to the inner ear, associated with zinc deficiency and symptoms resembling liver cirrhosis in humans.
42 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” This review examines the regeneration capabilities of skin, oesophagus, and oral mucosa, highlighting the oral mucosa's unique scarless healing properties and the potential of cell therapy to improve scar reduction in wound healing.