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Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

A TP63 gene mutation causes significant hair loss and mild skin, nail, and tooth abnormalities.

Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.

Researchers found 15 new genetic links to skin traits in Japanese women.

Minoxidil lowers blood pressure more effectively but has more side effects, so try hydralazine first.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

Ovarian steroid cell tumors should be considered in adults with hirsutism and high testosterone, with surgery as the main treatment.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Hirsutism greatly lowers the quality of life for Turkish women.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Insulin resistance significantly contributes to the development and severity of certain chronic skin diseases.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

Online forums help understand men's concerns about baldness and show the need for better support that changes how baldness is viewed.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

The conclusion is that a team of skin doctors and psychiatrists is needed to better treat patients with mind-skin disorders.

Cantú syndrome is caused by mutations in the ABCC9 gene.

Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.

A woman had a rare liver tumor causing male-like physical changes, highlighting the need for thorough checks when such symptoms appear.

Laser hair removal works well for people with dark hair and light skin, but it's less effective for light hair or dark skin; improvements are expected.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

Different hair removal methods have pros and cons, and more evidence is needed to prove laser treatments work.

Hair restoration surgery can have complications; success depends on patient education, careful planning, and proper execution.

Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.