research In Vitro Skin Permeation of Monoolein Nanoparticles Containing Hydroxypropyl β-Cyclodextrin/Minoxidil Complex
Nanoparticles improve minoxidil skin permeation, but more research needed for effective hair growth.
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research Finasteride Versus Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism
Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.
research Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia
Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.
research Whole Body and Regional Hemodynamic Effects of Minoxidil in the Conscious Dog
Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.
research Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment
Microneedles help treat hair loss by improving hair surroundings and promoting growth.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Psychocutaneous Diseases: A Review of Psychiatric Disorders with Skin Manifestations and Their Prevalence in Dermatological Settings
Many skin patients have mental health issues, but few dermatologists are well-versed in treating these conditions.
research Adrenal Disorders and the Pediatric Brain: Pathophysiological Considerations and Clinical Implications
Adrenal disorders can cause lasting brain and behavior issues in children.
research Guidelines for the Management of Androgenetic Alopecia (2010)
Use minoxidil for hair loss treatment, and finasteride for men.
research Original Research—Endocrinology: Comparison of the Steady-State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men
The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
research Systematic Review and Meta-Analysis of the Efficacy and Safety of Leflunomide and Methotrexate in the Treatment of Rheumatoid Arthritis
Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.
research Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-Regulate Their TLR-2 and TLR-4 Expression
ALA-photodynamic therapy helps reduce acne by causing acne cell death and lowering certain skin protein levels.
research Hair Problems in Women: A 1997 Study on Prevalence, Psychological Impact, and Treatment Approaches
Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.
research Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study
Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.
research Evaluation of the Predictive Capacity of DNA Variants Associated with Straight Hair in Europeans
Certain DNA variants can predict straight hair in Europeans but are not highly specific.
research Distribution and Localization of Hydrophobic and Ionic Chemical Groups at the Surface of Bleached Human Hair Fibers
Bleaching hair removes its protective top layer and exposes more hydrophilic groups, changing its chemical surface and affecting how it interacts with products.
research Early Onset and Novel Features in a Spinal and Bulbar Muscular Atrophy Patient with a 68 CAG Repeat
A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.
research Effect of Dutasteride 0.5 mg/day in Men with Androgenetic Alopecia Recalcitrant to Finasteride
Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
research Dorsal Skin Reactions of Hairless Dogs to Topical Treatment with Corticosteroids
Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.
research Clinical Efficacy and Safety of Low-Dose Flutamide Alone and Combined with an Oral Contraceptive for the Treatment of Idiopathic Hirsutism
Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
research Side Effects of 5-Alpha Reductase Inhibitors: A Comprehensive Review
5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
research Interventions for Female Pattern Hair Loss
Minoxidil effectively treats female pattern hair loss.
research Global Photographic Assessment of Men Aged 18 to 60 Years with Male Pattern Hair Loss Receiving Finasteride 1 mg or Placebo
Finasteride significantly improves hair growth but may cause sexual side effects.
research Androgenetic Alopecia in Adolescents: A Report of 43 Cases
Teen hair loss common in boys, linked to family history and mild symptoms.
research One of These Things Is Not Like the Others: The Idea of Precedence in Health Technology Assessment and Coverage Decisions
The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.
research Clinical Comparison of Extended-Release Divalproex Versus Delayed-Release Divalproex: Pooled Data Analyses From Nine Trials
Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.
research Validity of Trichoscopy in the Diagnosis of Primary Cicatricial Alopecias
Trichoscopy is a useful method for identifying primary cicatricial alopecias and their specific types.
research Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream
The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
research Maximum Efficacy of Finasteride Is Obtained Within 6 Months and Maintained Over 6 Years
Finasteride works best in 6 months and lasts 6 years.
research Photobiomodulation: The Clinical Applications of Low-Level Light Therapy
Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.