May 2025 in “Archives of Dermatological Research” Patient-reported hair improvements align with actual hair density changes, not hair width.
This study evaluated the effect of intralesional injections of lyophilized Platelet Derived Growth Factors in 42 patients with Peyronie's disease and found significant reductions in penile curvature and plaque size, along with improvements in Peyronie's Disease Questionnaire scores, suggesting a potential treatment role.
May 2025 in “Russian Journal of Allergy” This study reported that combining fexofenadine or ebastine with topical therapy significantly improved hair regrowth and reduced the severity of alopecia areata over 12 weeks compared to topical treatment alone.
May 2025 in “AlQalam Journal of Medical and Applied Sciences” In this study, researchers found that while low serum ferritin levels are common among women, there was no clear association between those low levels and diffuse hair loss in patients with female pattern hair loss and chronic telogen effluvium.
April 2025 in “Cosmetics” This study found that Clinopodium bolivianum essential oil, particularly in combing cream, demonstrated notable antioxidant activity, with potential applications as a natural antioxidant in cosmetic formulations.
In this study, researchers found that acne, melasma, vitiligo, and atopic dermatitis significantly impact anxiety, depression, loneliness, and quality of life, while alopecia does not have a significant effect.
April 2025 in “Düzce Tıp Fakültesi Dergisi” In this study, researchers examined vitamin D levels and blood count parameters in children and adolescents with non-scarring alopecia, finding significant vitamin D deficiency but no significant differences in deficiency or insufficiency across different types of alopecia.
April 2025 in “Antioxidants” In this study, the researchers found that the water-soluble fraction of Rhus semialata gall extract and its component Penta-O-Galloyl-β-D-Glucose promoted hair growth in human dermal papilla cells, and clinical trials supported these findings, showing improved hair density and appearance compared to placebo.
The researchers observed that in cases of alopecia areata with atypical features, histopathological confirmation may be necessary, as trichoscopic clues like loss of follicle ostia and vellus hairs were common, while typical features such as exclamation mark hairs were not always present.
April 2025 in “Pharmaceutics” This study examined three olive oil formulations of baricitinib for topical delivery in treating alopecia areata, finding that Oil A showed the highest skin retention and maintained skin integrity without irritation, suggesting its potential for further investigation.
April 2025 in “Journal of Cosmetic and Laser Therapy” This study found that QR678 Neo® significantly enhanced hair regrowth, density, and shaft diameter in males with advanced androgenetic alopecia undergoing hair transplant surgery, compared to a conventional method, making it a promising adjunct treatment option.
April 2025 in “ALEXMED ePosters” This study found that nanofat injections significantly improved scar characteristics, including collagen deposition, epidermal thickness, and vascularity, due to its anti-inflammatory and immunomodulatory properties.
April 2025 in “ALEXMED ePosters” This study reported that CXCL12 may have a dual role in alopecia areata, where decreased levels could impair angiogenesis and disrupt vascular support to hair follicles, while its overexpression might exacerbate autoimmune attacks on hair follicles, contributing to hair loss.
April 2025 in “Clinical Dermatology Review” In this study, researchers reported that dermatoscopy effectively differentiates between various types of alopecia and scalp disorders, offering a fast, minimally invasive diagnostic method that improves the standard of care and reduces the necessity for scalp biopsies.
April 2025 in “Journal of Advanced Pharmaceutical Technology amp Research” In this study, researchers reported that a combination treatment of Morinda citrifolia fruit extract and Averrhoa bilimbi leaf extract at specific concentrations significantly increased hair growth and weight in rabbits compared to controls, suggesting a potential anti-hair loss effect.
March 2025 in “Medical Science Journal for Advance Research” This study assessed miR-155 levels in the blood of patients with alopecia areata and found significantly different levels compared to healthy controls, indicating that miR-155 may play a significant role in the disease's pathogenesis.
March 2025 in “SKIN The Journal of Cutaneous Medicine” This study found that most TikTok content on platelet-rich plasma is created by laypeople and non-physician health care providers, and overall video quality is very poor, with content from dermatologists and physicians scoring higher.
March 2025 in “Archives of Dermatological Research” This study found that combined microneedling with minoxidil significantly improved hair count and diameter in patients with androgenetic alopecia, although more mild adverse events were reported compared to minoxidil alone.
March 2025 in “Salud Ciencia y Tecnología” This study found that patients with androgenetic alopecia were generally satisfied after receiving six sessions of PRP mesotherapy combined with nocturnal minoxidil 5% application.
March 2025 in “American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology” This study observed that individuals with hair loss had significantly higher levels of serum galanin, troponin, prolactin, and FSH, and lower levels of TSH, zinc, magnesium, copper, iron, and calcium compared to healthy controls, suggesting a potential role of these biomarkers in hair loss.
February 2025 in “Journal of Pharmacy And Bioallied Sciences” In this study, researchers found that autologous platelet-rich plasma injections significantly improved hair density and patient satisfaction in both male and female patients with androgenetic alopecia, with no major side effects reported.
February 2025 in “East African Scholars Journal of Medical Sciences” In this study conducted at Bangabandhu Sheikh Mujib Medical University, researchers reported that males with androgenetic alopecia had significantly higher levels of serum LH, prolactin, testosterone, DHEA-S, and free androgen index, and lower levels of serum FSH and SHBG compared to those without hair loss.
January 2025 in “Clinical and Experimental Optometry” This study found that men with androgenetic alopecia had significantly higher rates of dry eye symptoms and meibomian gland dysfunction compared to healthy controls, suggesting a potential link between the condition and these ocular issues.
January 2025 in “Diagnostics” In this prospective case-control study, researchers found that women with any phenotype of polycystic ovary syndrome exhibited increased retinal nerve fiber layer and choroidal thickness compared to healthy controls, with changes correlated to body mass index.
January 2025 in “International Journal of Endocrinology” This study found that the hydroalcoholic extract of the Dorema aucheri plant, especially at a 5% concentration, enhanced diabetic wound healing in male rats, improving re-epithelialization, collagen deposition, and neovascularization more effectively than other tested concentrations.
January 2025 in “International Journal of Trichology” This study found both topical spironolactone and topical minoxidil to be effective and safe treatments for female pattern hair loss, with mild to marked improvement observed over six months in both treatment groups, though more side effects were noted with minoxidil.
January 2025 in “International Journal of Trichology” This study found that patients with androgenetic alopecia had significantly higher COVID-19 severity compared to matched controls, suggesting a potential link between androgen pathways and disease severity. The authors suggest further research to validate this hypothesis and explore antiandrogen treatments for managing COVID-19 severity.
January 2025 in “International Journal for Research Trends and Innovation” This study assessed a herbal hair oil made from various plant ingredients, observing it supported hair growth and maintained stability for 45 days, with the phytochemical profile indicating the presence of saponins, sulfur, and ascorbic acid.
January 2025 in “International Journal of Medical Arts” This study found that a topical 1.0% sildenafil citrate solution significantly increased vellus and terminal hairs in women with female pattern hair loss without affecting hair thickness, suggesting it may be a promising treatment option.
January 2025 in “Journal of Medicinal Food” This abstract mentions that while synthetic drugs like minoxidil and finasteride for androgenic alopecia have side effects, the characteristics of popular natural alternatives, such as soybean, remain largely unreported, despite consumer preference for these products.