February 2024 in “Jurnal Sains dan Kesehatan” This study examined the antibacterial activity of Sansevieria trifasciata Prain. extracts and its ethyl acetate fractions, finding that both the extract and 40% fraction significantly inhibited bacterial growth, showing potential akin to ciprofloxacin in inhibiting S. aureus, E. coli, and P. aeruginosa.
2 citations
,
April 2024 in “Science & Technology Indonesia” In this study, extracts from the bark of Albizia saponaria, particularly the ethyl acetate fraction, showed significant antioxidant activity, potentially due to its high phenolic and flavonoid content, suggesting its usefulness as a source of antioxidants for pharmaceutical formulations.
4 citations
,
June 2020 in “Processes” This study suggests that G. sibiricum has potent aldose reductase inhibitory activity, primarily due to kaempferol rhamnosides, and may be further explored as a natural treatment for diabetes-related complications.
July 2026 in “Journal of Dermatologic Science and Cosmetic Technology” This study found that extracts from Terminalia bellirica enhanced dermal papilla cell viability, inhibited androgen-related pathways, and stimulated hair regrowth in a mouse model, suggesting potential for treating androgenetic alopecia through multi-target mechanisms.
2 citations
,
November 2009 in “DSpace (Federal University of Santa Catarina)” Brunfelsia uniflora has good antioxidant properties and moderate antibacterial activity.
This review reports that extracts from the plant Eclipta alba, traditionally used in herbal medicine, may promote hair growth by inhibiting TGF-β1 expression and functioning as a 5α-reductase inhibitor, potentially benefiting androgenic alopecia treatment.
January 2024 in “Natural product research” This study analyzed the bioactive compound profiles of Allium longisepalum from Iran, finding unique metabolites with potential antioxidant, allelopathic, antibacterial, anti-inflammatory, anticarcinogenic, and hair growth-enhancing properties, revealing the plant's chemical diversity and therapeutic potential.
4 citations
,
September 2024 in “Jurnal Pengolahan Hasil Perikanan Indonesia” In this study, researchers reported that compounds from Bruguiera gymnorhiza leaves showed anti-inflammatory potential in in silico analyses, with favorable drug properties and specific binding to the IKKβ receptor, suggesting possible development into anti-inflammatory drugs.
25 citations
,
December 2022 in “Indonesian Journal of Science and Technology” This study found that ethyl acetate extract from peanut stems demonstrated very strong antioxidant properties and moderate cytotoxic activity against MCF-7 cell lines in in-vitro and in-silico settings.
49 citations
,
October 2017 in “Nutrients” This study observed that the ethyl acetate extract of Equisetum debile showed high activity against 5α-reductase and lipid peroxidation with no cytotoxicity on dermal papilla cells.
1 citations
,
December 2022 in “International Journal of Science for Global Sustainability” This study found that Mitracarpus hirtus extracts showed potential antifungal activity against Tinea capitis in vitro, with ethylacetate extracts demonstrating the highest inhibitory effects.
61 citations
,
September 2010 in “Fitoterapia” This study found that the EtOAc extract of Tridax procumbens aerial parts significantly inhibited rat paw edema and COX enzyme activity, suggesting its potential anti-inflammatory properties.
23 citations
,
March 2019 in “Journal of Essential Oil Research” This study found a strong correlation between antioxidant activity and phenolic content in rosemary, influenced by bioclimatic and seasonal factors in different stages of Tunisia.
6 citations
,
October 2016 in “Food Science and Biotechnology” This study found that the water extract of Bituminaria bituminosa demonstrated the highest antioxidant activity and α-glucosidase inhibition among tested extracts, but no cholinesterase or tyrosinase inhibition.
March 2024 in “Journal of Pharmaceutical and Sciences” This study investigated the phytochemical composition and antibacterial and antioxidant activities of Zaleya pentandra extracts, finding high total polyphenol and flavonoid content and significant antibacterial effects, particularly in acetone extract, which may be suitable for developing antibacterial agents.
15 citations
,
June 2018 in “Journal of Chromatographic Science” This study successfully developed a method to measure four flavonoids from Platycladus orientalis leaves in rat plasma, which was used in a pharmacokinetic study on healthy rats.
This study suggests that ethyl acetate extract of Equisetum debile may be effective for functional food and nutraceutical use due to its strong 5α-reductase, IL-6 inhibition, and lipid peroxidation activities without cytotoxic effects.
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the ethyl acetate extract of Semecarpus anacardium leaves demonstrated cytotoxicity against MCF-7 cancer cells and induced apoptosis, suggesting potential as a cancer treatment with fewer side effects.
July 2021 in “Research Square (Research Square)” In this study, the ethyl acetate extract of Semecarpus anacardium Linn leaves was reported to induce cytotoxicity in cancer cells, cause cell cycle arrest, and suppress tumor growth in mice.
25 citations
,
July 2004 in “Experimental Dermatology” This study found that water-soluble extracts of Illicium anisatum promoted hair follicle elongation in cultured mouse vibrissae, suggesting potential use in hair growth products.
53 citations
,
July 2021 in “International Journal of Molecular Sciences” This study found that extracts from Geranium pyrenaicum show promising antioxidant, enzyme inhibitory, and antiviral activities, particularly the methanolic extract's antiviral activity against HSV-1.
13 citations
,
May 2021 in “Plants” This study found that the n-hexane fraction from Leea indica leaves significantly increased hair growth in mice and showed potential as a natural treatment for alopecia.
1 citations
,
November 2022 in “Research Society and Development” This review highlights the effectiveness of medicinal plants in treating symptoms of hair disorders, emphasizing their antifungal and antioxidant properties as supported by 23 selected studies.
33 citations
,
January 2009 in “Contraception” This review summarizes the use of chlormadinone acetate for hormone replacement therapy and contraception, highlighting its anti-androgenic effects, contraceptive efficacy, and clinical tolerability, without offering new clinical results.
64 citations
,
March 2006 in “Food Chemistry” In castrated rats, this study found that triterpenoids from Ganoderma lucidum inhibited both types of 5α-reductase and reduced prostate growth linked to testosterone but not dihydrotestosterone.
11 citations
,
December 2011 in “Revista Brasileira de Farmacognosia” In this animal study, petroleum ether and ethanolic extracts of Abrus precatorius seeds appeared to reverse androgen-induced alopecia in male albino rats by inhibiting the 5α-reductase enzyme, similar to finasteride.
4 citations
,
April 2019 in “Cosmetics” In this study, the bending stiffness of human hair was linked to the varying proportions of para-like versus ortho-like cortical cells within the hair fiber.
August 2024 in “Biomedical Journal of Scientific & Technical Research” This review discusses the role of steroid 5 alpha reductase 2 in converting testosterone to DHT and its association with conditions like benign prostatic hyperplasia and prostate cancer; it reports no new results.
21 citations
,
April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” This study suggests that gel containing OSF3 loaded in niosomes offers high transfollicular penetration for topical anti-androgenic alopecia treatment with minimal systemic effect.
1 citations
,
January 2008 in “Journal of Physiology & Pathology in Korean Medicine” In this study, topical extracts of Mylabris phalerata Pall. were observed to promote hair growth in mice, potentially indicating its benefit for hair growth activity at low doses.