research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
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research Targeted Delivery of a Poorly Water-Soluble Compound to Hair Follicles Using Polymeric Nanoparticle Suspensions
Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.
research Nuclear Factor I-C Regulates TGF-β-dependent Hair Follicle Cycling
Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.
research Large-Scale Cultivation of Transplantable Dermal Papilla Cellular Aggregates Using Microfabricated PDMS Arrays
Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
research The Effects of Particle Properties on Nanoparticle Drug Retention and Release in Dynamic Minoxidil Foams
Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
research Microencapsulated Human Hair Dermal Papilla Cells: A Substitute for Dermal Papilla?
Encapsulated human hair cells can substitute for natural hair cells to grow hair.
research Contribution of Androgens to Chronic Allograft Nephropathy Is Mediated by Dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
research Cloning, Expression, and Characterization of Rhesus Macaque Types 1 and 2 5alpha-Reductase: Evidence for Mechanism-Based Inhibition by Finasteride
Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
research Relationship Between Contact Time of Applied Dose and Percutaneous Absorption of Minoxidil From a Topical Solution
Longer contact time increases minoxidil absorption, but doesn't affect metabolism.
research Genetic Fate-Mapping Reveals Surface Accumulation But Not Deep Organ Invasion of Pleural and Peritoneal Cavity Macrophages Following Injury
Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.