Search

everythinglearnresearchcommunity

for

Search:↓

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Chitrak is a medicinal plant with health benefits like fighting microbes, reducing inflammation, and promoting hair growth, but it can be toxic and needs more research.

Finasteride reduces movement issues in Parkinson's disease rats.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Plumbago zeylanica has valuable medicinal properties but needs sustainable cultivation methods.

The dog's skin condition improved after removing a tumor that was causing hormone imbalances.

Analyzing bear poop helps measure their stress without harming them.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Indole-based compounds improved ovarian health in rats with PCOS, with L-Tryptophan and Tryptophol being most effective.

Caffeine intake during pregnancy and lactation can cause skin lesions in mother rats and their babies, not linked to cortisol levels.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Finasteride might affect memory by impacting cholinergic system.

OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.

Gut microbes significantly affect brain steroid levels.

Pregnancy and nursing increase certain brain activities in rats, but these changes disappear when the babies are taken away.

EGFR is essential for normal hair development and follicle differentiation.

Disabling the FGF5 gene in sheep leads to longer wool.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.

VDR regulation varies by tissue and is crucial for its biological functions.

Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.