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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Sebocytes play a key role in controlling androgen levels in human skin.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Spironolactone most effective for hirsutism, but has side effects.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Finasteride may help treat chronic CSC, improving vision.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Thyroid function affects skin health, with a complex interaction between the two.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Minoxidil effectively treats female pattern hair loss.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.