research Polymorphisms in Genes Involved in Steroidogenesis in the Development of Severe Acne
Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.
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research Major Approaches of Molecular and Physiopathological Mechanisms for Hormonal Treatment of Melasma: A Systematic Review
Estrogens and progesterone are key in regulating melasma pigmentation.
research Androgen Effects on the Skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research Does Estradiol Level in Platelet-Rich Plasma Improve Efficacy of Androgenic Alopecia Treatment?
Estradiol-rich plasma can increase hair density faster and more effectively in male pattern baldness treatment than regular plasma.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Blocking testosterone speeds up wound healing in males.
research Androgens Protect Against Apolipoprotein E4-Induced Cognitive Deficits
Androgens can help prevent memory problems caused by apoE4.
research Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females
Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
research Endocrinology of Transgender Medicine
Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
research Atrichia Caused by Mutations in the Vitamin D Receptor Gene Is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene
Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Clinical Management of Youth with Gender Dysphoria in Vancouver
Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation
TCDD speeds up skin barrier formation by increasing certain gene expressions.
research A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research Prolactin Delays Hair Regrowth in Mice
Prolactin slows down hair growth in mice.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research The Therapeutic Use of Androgens in Women
Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
research Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism
Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
research Human Type 3 5α-Reductase Is Expressed in Peripheral Tissues at Higher Levels Than Types 1 and 2 and Its Activity Is Potently Inhibited by Finasteride and Dutasteride
Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
research A Mouse Model of Androgenetic Alopecia
Mice with human gene experienced hair loss when treated with DHT.
research Evidence for 1,25-Dihydroxyvitamin D3-Independent Transactivation by the Vitamin D Receptor
The vitamin D receptor can work without its usual activating molecule.
research Androgens Induce Sebaceous Differentiation in Sebocyte Cells Expressing a Stable Functional Androgen Receptor
Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
research Baldness, Acne, and Testicular Germ Cell Tumors
Men with testicular cancer were less likely to experience baldness and severe acne.
research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research Hormonal Therapies for Acne
Hormonal treatments can improve acne, but they come with potential side effects and risks.
research Alterations in Hair Follicle Dynamics in Women
Hormonal changes after childbirth and menopause can lead to women's hair loss and facial hair growth, with a need for better treatments.
research Hormone Therapy in Acne
Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
research Anti-Androgen Treatments for Hirsutism and Acne in Women of Childbearing Age
For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Frontiers in the Neuroendocrine Controls of Hair Growth
Hair growth and health are influenced by stress and hormones.
research 5α-Reductase Isozymes and Aromatase mRNA Levels in Plucked Hair from Young Women with Female Pattern Hair Loss
Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.