research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
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research The Pathophysiology of Polycystic Ovary Syndrome: Understanding PCOS and Its Endocrinology
The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
research Finasteride
Finasteride effectively treats baldness but may cause sexual side effects.
research Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives
Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
research Frontal Fibrosing Alopecia: A Retrospective Review of 19 Patients Seen at Duke University
Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.
research Hormones and the Pilosebaceous Unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
research Testosterone Supplementation for Aging-Associated Sarcopenia
Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
research Sex Hormone-Binding Globulin: An Important Biomarker for Predicting PCOS Risk - A Systematic Review and Meta-Analysis
Lower SHBG levels may increase the risk of PCOS.
research Intracrinology and the Skin
DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
research Eating Disorders: Progress and Challenges
Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.
research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
research Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss
Aromatase gene variation may increase female hair loss risk.
research Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome: A Six-Month, Open-Label Randomized Study
Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
research Menstrual Disorders in Adolescents
The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
research Female Gonadal Function Before and After Treatment of Acromegaly
Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.
research Potential Adverse Effects of Long-Term Testosterone Therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research The SAHA Syndrome: Overview and Classification
SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.
research Polycystic Ovary Syndrome and Its Impact on Health
PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
research The Modulatable Stem Cell Niche: Tissue Interactions During Hair and Feather Follicle Regeneration
The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
research Role of Oxidative Stress in Polycystic Ovary Syndrome
Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
research C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
research Functional Complexity of Hair Follicle Stem Cell Niche and Therapeutic Targeting of Niche Dysfunction for Hair Regeneration
Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research TGFβ and Cancer Metastasis: An Inflammation Link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research Association of Biochemical Hyperandrogenism with Type 2 Diabetes and Obesity in Chinese Women with Polycystic Ovary Syndrome
High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.
research Hyperandrogenism in Polycystic Ovarian Syndrome and Role of CYP Gene Variants: A Review
Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
research Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee
Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.
research Tamoxifen for Flutamide/Finasteride-Induced Gynecomastia
Tamoxifen effectively treats gynecomastia without causing impotence.
research The Safety of 52 Weeks of Oral DHEA Therapy for Postmenopausal Women
Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.