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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Noggin is necessary to start the hair growth phase in skin after birth.

Androgens can both increase and decrease hair growth in different parts of the body.

PGD2 stops hair growth and is higher in bald men with AGA.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Sebocytes play a key role in controlling androgen levels in human skin.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Androgens can help prevent memory problems caused by apoE4.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Oestrogens are key for bone growth during puberty in both boys and girls.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.