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Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Noggin is necessary to start the hair growth phase in skin after birth.

PGD2 stops hair growth and is higher in bald men with AGA.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Sebocytes play a key role in controlling androgen levels in human skin.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.