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Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

The PLP2 gene affects cashmere fiber quality in goats and is linked to hair growth and loss.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

Immune cells are crucial for hair growth and preventing hair loss.

Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.

Excess androgens may cause PCOS, not just be a symptom.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.

Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.

Estrogens and progesterone are key in regulating melasma pigmentation.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

Melatonin protects skin and hair from damage and stress by acting as an antioxidant and influencing cell growth.

The Hairless gene is crucial for healthy skin and hair growth.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Prolactin may affect hair growth differently based on gender and scalp area.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.