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Melatonin directly affects mouse hair follicles and may influence hair growth.

Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

No treatment fully prevents hair loss from chemotherapy yet.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

Minoxidil and finasteride effectively treat hair loss.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.