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New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

Certain long non-coding RNAs are important for controlling hair growth cycles in sheep.

Melatonin affects certain genes and pathways involved in cashmere goat hair growth.

High testosterone increases heart disease risk in women with PCOS.

The document explains how male reproductive hormones work and affect the body.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Monitoring for adverse effects in clinical treatments is crucial.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

Men with more vanadium in their blood and who drink less soy milk are more likely to have hair loss.

The PLP2 gene affects cashmere fiber quality in goats and is linked to hair growth and loss.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.