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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Testosterone therapy increases bone density in older men with low testosterone levels.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The Rotterdam Study aims to understand various diseases in older adults.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Liposomes could improve how skin care products work but are costly and not very stable.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Minoxidil and finasteride effectively treat hair loss.

Mutant mice help researchers understand hair growth and related genetic factors.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.