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Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Dutasteride and finasteride affect different cell types differently.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.

Estrogen helps keep skin healthy and may make women look younger and more attractive.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Treatments for hair loss vary, but cell-based options may be the future.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Hair lotions with 17 alpha-estradiol can reduce hair loss but won't regrow new hair.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.