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Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Tianma Gouteng decoction may help prevent hair loss and promote hair growth.

Sansevieria trifasciata Prain shows promise for treating hair loss by inhibiting androgen receptors.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Wnt4 protein makes the outer skin layer thicker in burn wounds by turning on a specific healing pathway and loosening the connections between skin cells.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Neurosteroids show promise for treating epilepsy and more research is needed.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

The vitamin D receptor can work without its usual activating molecule.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.