research Distinct Transcriptional Profiles of the Female, Male, and Finasteride-Induced Feminized Male Anogenital Region in Rat Fetuses
Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
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research Relation of Urinary Stone Disease with Androgenetic Alopecia and Serum Testosterone Levels
Balding and low testosterone increase risk of urinary stones.
research Activin B Promotes Initiation and Development of Hair Follicles in Mice
Activin B helps start and grow hair follicles in mice.
research Diagnosis and Management of Infertility Due to Anovulation
The conclusion is that lifestyle changes and weight loss are first-line treatments for infertility due to anovulation, with various medications and assisted reproductive technologies as additional options.
research Clinical Impact of Molecular Diagnostics in Endocrinology
Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.
research Caring for Women with Polycystic Ovary Syndrome
Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Alopecia: Managing the Basics
The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.
research Foreword
The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin
Noggin is necessary to start the hair growth phase in skin after birth.
research Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research Linking Diet to Acne Metabolomics, Inflammation, and Comedogenesis: An Update
Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
research Polycystic Ovarian Syndrome: Comprehensive Overview and Management Approaches
Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
research Inhibition of SARS-CoV-2 Entry Through the ACE2/TMPRSS2 Pathway: A Promising Approach for Uncovering Early COVID-19 Drug Therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research Keratinocyte Growth Inhibition Through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells
Androgens slow hair growth by altering Wnt signaling in balding cells.
research The Senescence–Stemness Alliance: A Cancer-Hijacked Regeneration Principle
Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
research Estrogen Functions in Skin and Skin Appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research A Review of the Treatment of Male Pattern Hair Loss
Finasteride and minoxidil work best together for hair loss.
research Expression and Roles of Steroidogenic Acute Regulatory (StAR) Protein in Non-Classical, Extra-Adrenal, and Extra-Gonadal Cells and Tissues
The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
research Hair: What Is New in Diagnosis and Management?
Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
research Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia
Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Differential Effects of Melatonin as a Broad Range UV-Damage Preventive Dermato-Endocrine Regulator
Melatonin protects skin against UV damage by regulating various cellular processes.
research The VEGF +405 G>C 5' Untranslated Region Polymorphism and Risk of PCOS: A Study in South Indian Women
The VEGF +405G allele may increase the risk of PCOS in South Indian women.
research The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease
Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
research Hedgehog And Gli Signaling In Embryonic Mammary Gland Development
Hedgehog signaling is crucial for mammary gland development over hair follicles.
research Male Hormonal Contraception: Looking Back and Moving Forward
New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Current Evaluation of Amenorrhea
Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.