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Patients with advanced breast cancer and high hormone receptor levels who had surgery for ovarian/pelvic metastases lived longer, especially if they had high estrogen receptor levels.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Estrogen helps prevent artery plaque by stopping monocyte capture in blood vessels.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Estrogen and progesterone don't directly affect hair growth in androgenic alopecia and alopecia areata.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.

The effects of estrogen on human hair growth are unclear and need more research.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The effects of estrogen on human scalp hair growth are unclear and need more research.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Oxytocin receptors are found in skin cells near touch and pain neurons.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.