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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Glioblastoma cells can make androgens, which might help the tumor grow.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Estrogen and its receptors play a key role in hair growth, with differences between males and females.

CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

ROR-alpha may increase the growth of certain breast cancer cells by boosting aromatase, which could affect breast cancer prognosis.

Dihydrotestosterone increases arterial stiffness in female mice without changing blood pressure or aortic wall thickness.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The study suggests a possible increase in androgen receptors in patients with frontal fibrosing alopecia, but more research is needed.

The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.

Alopecia patients have less GPER-1, which might affect hair loss.

Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Estrogen helps prevent artery plaque by stopping monocyte capture in blood vessels.