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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Alopecia patients have less GPER-1, which might affect hair loss.

17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Dutasteride and finasteride affect different cell types differently.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Hormonal therapies help treat female hair loss, but results are slow and vary.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Chinese black tea extract helped mice grow hair, especially when combined with capsaicin.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.