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Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

A woman with severe angioedema improved significantly after treatment with rituximab.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.

New treatments for PCOS focus on managing symptoms and improving fertility.

A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.

Increased PPARGC1α relates to hair thinning in common baldness.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

Two teenage boys lost hair after taking a drug for growth, which was not a known side effect for kids.

Formononetin, found in red clover, may treat hair loss with fewer side effects.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.

Women with hair loss have higher androgen levels, while men with early balding have altered androgen ratios.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Removing part of the vitamin D receptor stops vitamin D from working properly.