Search

everythinglearnresearchcommunity

for

Search:↓

Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Some synthetic carbohydrate receptors, especially compounds 3 and 15, show strong potential for treating Zika virus.

The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Women with PCOS may have a higher risk of respiratory and ear infections due to slower nasal mucociliary clearance.

FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Finasteride helps treat hair loss by blocking enzyme activity.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Taking vitamin C and vitamin E twice a day can help prevent sunburn and DNA damage from UVB exposure.

Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Finasteride exposure harms tadpole reproduction and hormone balance.

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Estrogen can temporarily slow down hair growth but this can be reversed.

Human keratinocytes do not naturally respond to androgens.