Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study used computational modeling to identify key genes and miRs involved in cardiac aging, finding a strong relationship supported by literature and some experimental validation in aged mouse hearts.

In this study, researchers used a 3D in vitro organ culture system to show that rifampicin-loaded lipid nanocapsules can penetrate hair follicles more effectively than free rifampicin, highlighting the potential advantage of nanocarrier-based antibiotic treatments for follicular infections.

This study found that testosterone increased seizure severity in mice and rats, with its neurosteroid metabolites playing a role in modulating seizure susceptibility.

In this study, significant elevations of DHA and testosterone were associated with pubic hair development and voice changes in boys during puberty.

This study found that exposing seasonally anestrous mares to extended light periods led to the earlier onset of endocrinologically normal estrous cycles, potentially allowing earlier breeding and foaling.

This study found that topical estradiol inhibits hair growth in mice by preventing the hair follicle's transition from resting to growth phase, a process reversible with an estrogen receptor antagonist.

This study found that testosterone modulates vascular cell behavior through direct actions that do not rely on its conversion to estradiol.

This study found that low doses of leuprolide effectively suppressed serum estradiol and LH response, while higher doses were needed to suppress testosterone and reduce hair growth in hirsute women.

This study found that oral estradiol was generally effective in achieving target 17-β estradiol levels in transgender women, but often failed to suppress testosterone adequately, with variability in individual responses.

In this retrospective study, cyproterone acetate treatment in late-pubertal trans-girls was found to be generally safe and led to mild feminizing effects, with more rapid feminization occurring when combined with estrogens.

This report describes a case of meningioma in a transwoman treated long-term with estradiol and cyproterone acetate, suggesting possible concern over female sex steroids and meningioma risk.

This study found that the effectiveness of 17-beta-estradiol in inhibiting hair growth depends on its application method, and noted significant sex differences in response to 17-alpha-estradiol in male and female mice.

This study found that early treatment with estradiol or dihydrotestosterone significantly reduced prostate adenocarcinoma development in Lobund-Wistar rats, while later treatments were ineffective.

This study concluded that exposing anestrous brood mares to a 16-hour photoperiod in early December led to endocrinologically normal estrous cycles starting within two months, enabling earlier breeding and foaling.

In this study, high concentrations of dihydrotestosterone and testosterone reduced the growth of human hair follicle cells in vitro, while high estradiol levels increased their growth.

This study found that dutasteride completely suppressed the formation of 5alpha-dihydro metabolites in cultured human skin cells, suggesting its potential use in acne and androgenetic alopecia.

This study found weak to very weak correlations between estradiol, progesterone, and testosterone levels in the cerebrospinal fluid and serum of males without cerebral disorders.

In this study, 17β-estradiol increased VEGF production in differentiated THP-1 cells, while dihydrotestosterone counteracted this effect by modulating adenylate cyclase activity.

Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.

This study reported that applying natural or artificial folliculoid compounds to mouse skin caused estrous-like changes in internal sex organs, but did not lead to cancerous skin changes.

This study found that progesterone levels were higher and increased significantly throughout pregnancy, contrasting with stable levels in non-pregnant women.

This study suggests that estrogen synthesis from estrone sulfate significantly influences hair growth regulation, with variations based on the hair growth phase, gender, and age.

This study found that noninflammatory alopecia in dogs can be caused by exposure to estradiol gel used by their owners for postmenopausal symptoms, with hair regrowth observed after minimizing exposure.

This study found that Hedgehog signaling likely contributes to cervical carcinogenesis, and while itraconazole reduced growth in mice, it did so through pathways other than inhibiting Hedgehog signaling.

Testosterone, DHT, and estradiol significantly affect hair cell growth.

In this study, 150 kHz electromagnetic radiation reduced the number and size of follicular cysts in a rat model of polycystic ovary syndrome without causing significant morphological damage to developing follicles.

In this study, an ultra-low dose combination of estradiol and dydrogesterone significantly reduced hot flushes and improved health-related quality of life among a multi-ethnic population of postmenopausal women, with no notable difference in serious adverse events compared to placebo.

This study found that the E2-ANGPT2 pathway is involved in hair follicle regulation and that ANGPT2 treatment increased hair density in modeled female pattern hair loss, suggesting potential therapeutic use.

This study found that testosterone and dihydrotestosterone inhibit the growth rates of hair bulb papilla cells and root sheath fibroblasts, especially at higher doses, while estradiol was ineffective.