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Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.

Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.

Natural products like propolis are causing more skin allergies, and certain skin treatments and medications have various side effects and risks.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

Use minoxidil for hair loss treatment; assess results after 6 months.

Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Estradiol stops hair growth in mice, but an antagonist can reverse this effect.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.

Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Hormone levels in hair change during pregnancy, with progesterone increasing significantly compared to non-pregnant women.

Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

Adjusting estradiol-ANGPT2 levels can promote hair growth in female pattern hair loss.

Topical finasteride works faster and better than 17α-estradiol for postmenopausal hair loss.