31 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
4 citations,
January 2017 in “Acta Endocrinologica” Finasteride and metformin both help treat PCOS, but using them together works best.
1 citations,
March 2022 in “Clinical and Experimental Obstetrics & Gynecology” Ovarian volume is significantly related to higher levels of certain hormones in Korean women with PCOS.
31 citations,
September 2020 in “Clinical endocrinology” Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
January 2020 in “대한피부과학회지” Dutasteride effectively increases hair density in women with hair loss.
January 2008 in “Dermatology Online Journal” Hormonal therapy like cyproterone acetate and spironolactone may help female hair loss, but more research is needed, especially for pre-menopausal women.
16 citations,
February 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.
6 citations,
October 1993 in “Endocrinology” Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
1 citations,
January 1986 in “Journal of Steroid Biochemistry” Women with excessive hair growth or polycystic ovary disease may more often carry a gene variant for 21 hydroxylase deficiency.
30 citations,
August 1992 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect hormone levels in normal men.
34 citations,
May 2007 in “Neuroscience” Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.
57 citations,
February 2007 in “International Journal of Cancer” A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.
131 citations,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
3 citations,
October 2004 in “International journal of gynaecology and obstetrics” Finasteride doesn't change polycystic ovary size or cyst number, suggesting testosterone's role in their appearance.
18 citations,
November 1998 in “Comparative biochemistry and physiology. Part A, Molecular & integrative physiology” Changes in prolactin and DHEA levels are not required for the start of mink hair growth cycles.
8 citations,
January 2018 in “Science of the total environment” Australian fur seals' fur shows high levels of pollutants, which may be linked to hair loss in young female seals.
2 citations,
July 2022 in “Frontiers in Medicine” Combining minoxidil with microneedling or spironolactone is more effective for female hair loss than using minoxidil alone.
6 citations,
August 1993 in “Archives of Dermatology” A woman's hair changed to a dry, tangled texture that's hard to comb after treatment with spironolactone, suggesting the medication might cause such hair changes.
May 2021 in “Journal of Advances in Internal Medicine” A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.
54 citations,
February 2010 in “British Journal of Dermatology” Hair loss in women may have causes other than hormones.
53 citations,
May 2010 in “PubMed” Spironolactone helps regrow hair in women with hair loss.
17 citations,
March 2006 in “Journal of Cosmetic Dermatology” Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.
22 citations,
June 1993 in “Calcified Tissue International” Women with hyperandrogenic amenorrhea have similar bone density to healthy women but lower than androgenized women without amenorrhea, and high DHEAS levels might affect bone density.
March 2006 in “Archives of Dermatology” Topical steroids help Erosive Lichen Planus, finasteride with birth control aids Female Pattern Hair Loss, young age helps Occupational Hand Eczema prognosis, quitting smoking is key for Diffuse Dermal Angiomatosis, and a 3-site Botulinum Toxin A injection is effective for glabellar wrinkles.
January 2008 in “The Year book of endocrinology” Gene variant linked to prostate cancer, hormone levels, and hair loss.
22 citations,
February 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” An 81-year-old woman's severe male hormone symptoms were caused by an ovarian tumor, which was treated with surgery.
22 citations,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
37 citations,
September 2018 in “The Journal of Clinical Endocrinology and Metabolism” Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.
3 citations,
November 2013 in “PubMed” April 2022 in “Medical Molecular Morphology”