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Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.

Muscles can make their own androgens, which may help muscle growth.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

More research is needed to understand how testosterone is maintained in adult males.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

The seed extract of Lepidium sativum L. can potentially treat hair loss, showing effects similar to 5% minoxidil.

Estradiol stops hair growth in mice, but an antagonist can reverse this effect.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.

Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.