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Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.

A male with aromatase deficiency improved bone health with estradiol treatment.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Ovariectomized mice mimic postmenopausal hair loss, and estradiol helps maintain hair density.

A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.

Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.

Cyproterone acetate combined with ethinyl estradiol significantly reduced hirsutism in women.

The oral contraceptive with ethinyl estradiol and chlormadinone acetate is effective in treating moderate acne.

Non-daily contraceptives cause fewer side effects and are more satisfying to women, and certain oral contraceptives can treat acne and seborrhoea, with a combination of chlormadinone acetate and ethinyl estradiol being highly effective and safe.

Cyproterone acetate with ethynyl estradiol significantly improved acne and seborrhea in women, but was less effective for hair loss and excessive hair growth.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Estrogen affects hair growth and skin cell multiplication.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Finasteride effectively treats baldness but may cause sexual side effects.

Spironolactone is effective in treating excessive hair growth in women.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Women have unique stroke risks due to hormones, contraceptives, pregnancy, and menopause.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.