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This study synthesized and characterized new 2-hydroxypyrrolidine/piperidine derivatives using FeCl₃·6H₂O as a catalyst, but it reports no biological or clinical results.

This study observed that repeated perm treatments decrease disulfide bonds in hair due to their conversion largely into cysteic acid, affecting the waving efficiency depending on the reduction agent used.

This study found that minoxidil exhibits preferential solvation by water in both water-rich and ethanol-rich solvent mixtures.

This review discusses the potential carcinogenic effects of anabolic androgenic steroids, particularly regarding Leydig cell tumors, and highlights the need for preventive information campaigns due to associated health risks.

This review discusses the role of TGM3 in skin and hair follicle biology, human tumor pathology, and genetic abnormalities, and reports no novel results; the authors highlight its potential as a cancer diagnostic biomarker.

This study observed that lipids in human hair accumulate in specific areas and do not significantly impact water permeability, highlighting the utility of AFMIR for studying complex biomaterials.

This review discusses new research on the role of retinoids in skin and hair health and reports no clinical results.

This study reports that patients with specific MFN2 mutations, including p.Arg707Trp, exhibit significant upper body fat overgrowth with suppressed leptin production, suggesting tissue-selective mitochondrial dysfunction and potential therapeutic targets.

This study observed that inducible deletion of the Ugcg gene in mouse epidermis led to a significant reduction in GlcCers and epidermal POS-Cers, causing impaired skin barrier function and delayed wound healing.

In this study, researchers synthesized new surfactants with hair repair properties, finding that they effectively restored the hydrophobic barrier of damaged hair and improved combing ease compared to untreated hair, highlighting their potential in haircare products.

TEDAR is crucial for skin cell differentiation and barrier formation.

This study found that poly(butylene citramalate-co-butylene succinate) copolymers exhibit high toughness, recyclability, degradability, and biocompatibility, achieving complete wound healing with skin and hair follicle regeneration in 7 days.

This review discusses the common occurrence of docetaxel-induced hair loss in cancer patients, including permanent cases, and highlights current and experimental strategies like scalp cooling, minoxidil, and new clinical trials for managing and preventing this side effect.

In this study, researchers found that knockdown of ABCA5 in primary human hair follicle keratinocytes disrupted cholesterol homeostasis and transportation, suggesting its potential role in hair growth disorders by affecting intracellular cholesterol compartmentalization and LXR-mediated transcriptional activity.

This study suggests that specific mutations in the MFN2 gene, including the p.Arg707Trp allele, can result in tissue-selective mitochondrial dysfunction leading to excessive upper body fat growth and low leptin levels.

In this study, the researchers reported that while both propylene glycol and sodium lauryl sulfate enhanced finasteride's skin deposition, ethanol was the only effective enhancer of finasteride's permeation through the skin.

This study found that oxidative treatment with peracetic acid dissociates some disulfide bonds in human hair fibers while maintaining the crystalline structure, suggesting different mechanisms stabilize different regions of intermediate filaments.

This study examined finasteride degradation under stress conditions, identifying three unique degradation products in acidic environments, providing insights into impurity profiling and quality control for finasteride formulations.

This study found that hydroxycinnamate derivatives, especially a compound named 10a, effectively inhibited SRD5A1 activity and protein expression in cell assays, suggesting potential for treating androgen-related conditions.

This study reports an improved and more cost-effective 7-step synthesis method for finasteride with an overall yield of 20.01%.

The researchers reported that epitestosterone treatment reduced eicosanoid levels generated by cyclooxygenases and lipoxygenases in rabbit liver samples with carrageenan-induced inflammation.

In this study, the novel thiol-Michael click perming molecule, MA2-CySS, achieved repeatable perming with reduced oxidative damage, preserving hair keratin's structure while maintaining efficiency comparable to traditional oxidative methods.

This study discusses that permanent hair straightening can be achieved at neutral or acidic pH conditions, with varying effects on cystine and lanthionine levels, by inducing supercontraction of the hair fiber.

This paper reviews the surface degradation of hair and describes how combining 18-MEA with specific surfactants can maintain hydrophobicity on bleached and weathered hair surfaces.

This study found that Soxhlet extraction is more effective at removing the toxin mimosine from Leucaena leucocephala, and mimosine shows promise as a biodiesel additive due to its antioxidative properties.

This study found that photochemical and cosmetic chemical oxidation of hair causes surface damage by delipidation and acid formation, which can be characterized and quantified using microfluorometry and X-ray photoelectron spectroscopy.

In this study, all stereoisomers of cyoctol were synthesized and tested, revealing that contrary to initial patent claims, cyoctol does not function as an anti-androgen.

This study introduces a novel visible light-mediated intramolecular [2+2] cycloaddition process that forms 6-azabicyclo[3.1.1]heptanes, offering a new synthesis route for bioisosteric mimetics used in drug discovery, potentially expanding medicinal chemistry applications beyond traditional limitations.

This study reported that while no synthesized compounds surpassed finasteride in 5α-reductase inhibitory activity, certain 4-azasteroid-2-oximes exhibited notable inhibition.