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Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

High energy boosts root hair growth in plants, while low energy stops it.

Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.

High doses of tryptophan may cause eosinophilic fasciitis.

Leucaena leucocephala is nutritious but needs careful processing to remove toxins.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.

The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.

Dates may improve heart health, fight infections, protect kidneys, reduce inflammation, support pregnancy, promote dental and bone health, enhance mental function, and have anti-cancer properties, and are also beneficial for skin and hair care.

Herbal hair oils help with hair problems and are safer than synthetic products.

Root hairs are key for developing cereals that can fertilize themselves with nitrogen.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Frog skin cells need the protein desmoplakin for proper development and cell layer formation.

The document explains how male reproductive hormones work and affect the body.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.