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New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.

Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Sulfasalazine can cause severe allergic reactions leading to long-term autoimmune issues like hair loss and skin discoloration.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

A woman's liver problems improved after she stopped taking spironolactone.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

An 11-month-old boy with Menkes disease had severe brain shrinkage and abnormal blood vessels, and didn't respond well to treatment.

Finasteride helps treat hair loss by blocking enzyme activity.

Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.

Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

A new non-invasive method can analyze skin mRNA to understand skin diseases better.

Storing hair follicles in special buffers with added protective substances can increase hair growth and reduce cell death.

Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.

The conclusion is that managing cholesterol is important for women, especially during pregnancy, breastfeeding, and with PCOS, and involves regular screening and careful treatment choices.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.

Quinoline alkaloids from Cinchona may help treat cancer, diabetes, fungal infections, and promote hair growth.

Itraconazole-loaded nanoparticles are more effective and less toxic for treating fungal infections than conventional oral itraconazole.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.