Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study provides evidence-based recommendations for the off-label use of topical vitamin D in treating certain skin conditions, but highlights the need for higher quality studies for further validation.

This review discusses the identification and roles of different epidermal stem cell types in skin homeostasis and repair, and reports no new experimental findings.

In this study, researchers found that deleting Caspase-9 in hair follicle stem cells delayed apoptosis, leading to accelerated wound repair and new hair follicle regeneration by maintaining apoptotic cells as signaling centers.

In this randomized clinical trial, the authors reported that adipose-derived stem cell constituent extract topical solution increased hair density and thickness in patients with androgenetic alopecia over 16 weeks compared to placebo.

This study found that morroniside enhanced hair follicle growth and transition through the Wnt/β-catenin signaling pathway in a mouse model, suggesting its potential as a treatment for hair loss.

This study found that in mice lacking EGFR, elevated Wnt signaling disrupts hair follicle development by affecting cell proliferation and differentiation, revealing a critical role for EGFR in regulating these processes.

This review summarizes common skin-related side effects of BRAF inhibitors and immunotherapy in advanced melanoma treatment, reporting no new clinical findings, and emphasizes consensus management to improve patient outcomes.

This review suggests that PRP injections may be effective in promoting hair regrowth, reducing hair loss, and increasing hair thickness in patients with androgenic alopecia.

This article reviews the role of R-spondins and their receptors in bone development and metabolism, highlighting their potential modulatory effects and clinical implications for treating bone loss diseases, but reports no new clinical results.

This study suggests that an extract from Malva verticillata seeds could help treat hair loss by modulating the Wnt/β-catenin pathway in cultured human dermal papilla cells.

This study found that arctiin, a compound from Arctium lappa, demonstrated protective effects against oxidative stress-induced dysfunction in human hair dermal papilla cells, suggesting potential therapeutic use for alopecia.

This study observed that 71% of chronic myeloid leukemia patients treated with second-generation tyrosine kinase inhibitors experienced adverse cutaneous reactions, which were generally less severe than those caused by imatinib.

This review examines the roles of Hedgehog and Gli proteins in mouse embryonic mammary development and suggests that Gli3-repressor-mediated off-state of Hedgehog signaling determines mammary fate over hair follicle fate.

Gepant medications for migraines show varied safety profiles in this study, with specific adverse events reported across systems like gastrointestinal and skin disorders, highlighting the need for tailored treatment and monitoring.

This review discusses the potential of ozone therapy as an adjuvant to radio-chemotherapy for cancer patients, noting enhanced treatment effects and improved quality of life, but it presents no new research findings.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

In this study, fractional laser treatment was observed to reverse age-related gene expression changes in skin and enhance dermal remodeling, further improved by multiple treatments.

This review found that platelet-rich plasma therapy improved hair growth and thickness in most studies on alopecia, with the highest improvement seen when combined with Minoxidil.

This review discusses the potential benefits of flavonoid-containing botanicals, such as Panax ginseng, in reducing hair loss and promoting hair growth, but reports no new experimental results.

This review discusses the role of lysophosphatidic acid in skin physiology and pathology, highlighting its significance in processes like wound healing and hair follicle development, but reports no new clinical findings.

This article discusses the discovery of the first known menstruating rodent, the spiny mouse, and proposes that a significant increase in progesterone during the luteal phase is a unique feature of menstruating species, but reports no new experimental results.

This review discusses the broader roles of angiogenic factors, like VEGFs and FGFs, beyond angiogenesis, highlighting their involvement in various biological and pathological processes.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

This review discusses the potential roles of prostaglandin D2 and its receptor CRTH2 in various diseases beyond allergies and asthma and reports no new clinical results.

In this study, full-size KRT81 was expressed in both normal breast epithelial and breast cancer cells, and contributed to the migration and invasion abilities of breast cancer cells.

This study found that the growth of hair ice on dead wood requires the biological activity of a winter-active fungus, specifically Exidiopsis effusa, which shapes and stabilizes the ice structures.

This study identified new potential targets and indications for several marketed drugs using in silico profiling, suggesting opportunities for drug repositioning.

This review discusses the dermatology of nonhuman primates and emphasizes the need for a cohesive approach to study and report their dermatologic diseases, without assuming similarities to human or other veterinary conditions.

This study found that extracellular ATP released from UVB-irradiated keratinocytes promotes melanin production through the P2X7 receptor, indicating a role for ATP-P2X7 signaling in UV-induced melanogenesis.

This review suggests that platelet-rich plasma is a low-risk treatment for androgenic alopecia with good patient satisfaction and positive objective outcomes, but further research is needed to refine methods and standardize outcome measurements.