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High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

lncRNAs may regulate hair follicle development in Hu sheep.

Researchers found genes linked to hair loss in male giant pandas.

Researchers identified genes that may affect hair growth in Cashmere goats.

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.

Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.

Applying InlB321/15 to wounds sped up healing in mice.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Targeting the actin cytoskeleton could improve skin healing and reduce scarring.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.

Chicken feather gene mutation helps understand human hair disorders.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.