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A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.

A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

The lentiviral array can monitor and predict gene activity during stem cell differentiation.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.

Activating δ-opioid receptors can help hair grow.

FGF12 is important for hair growth and could be targeted for hair loss treatment.

Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.

The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Finasteride improves heart function and repairs damage after heart attack in mice.

Using skin stem cells and certain molecules might lead to scar-free skin healing.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Metformin may help treat neuroendocrine tumors.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Salvianolic Acid B helps hair grow by reducing cell stress and increasing blood flow to hair follicles.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.