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Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

HSD11b1 affects skin nerves and increases non-histaminergic itch.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Aging causes skin stem cells to work less effectively.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

PRP shows promise for hair loss treatment, with three initial monthly injections and maintenance every 3-6 months.