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This study found that a 14-day treatment with proxalutamide significantly reduced the 28-day mortality rate in hospitalized COVID-19 patients compared to placebo, with greater benefits observed among those who adhered to the treatment.

This study concluded that among men with normal testosterone levels, a small increase in serum dihydrotestosterone may reduce symptoms of hypogonadism, suggesting its potential diagnostic use after ruling out hypogonadism.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.

Finasteride may help reduce tic severity in male Tourette syndrome patients.

In this article, the authors reviewed essential terminology and recommendations for creating a welcoming healthcare environment for transgender patients and providing gender-affirming therapy, emphasizing the unique health needs and disparities faced by this population.

This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.

This article presents guidelines developed by a multidisciplinary expert panel for the care of adolescent transgender and non-binary individuals with gender dysphoria, emphasizing individualized, affirmative care to enhance well-being and quality of life.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.

This study found that while new treatments like Optilume, Rezum, and Aquablation have minimal risks of sexual dysfunction, they offer less improvement in lower urinary tract symptoms compared to traditional surgeries like TURP, though Aquablation does reduce ejaculatory dysfunction more effectively than TURP.

This review suggests that dihydrotestosterone pretreatment may improve cosmetic outcomes in hypospadias repair, but more randomized trials are needed to determine its effectiveness due to currently limited evidence.

This systematic review synthesizes the current state of drug repurposing, revealing its potential in various therapeutic areas like oncology and infectious diseases through insights from mechanistic studies and real-world evidence, and discusses emerging tools and challenges in the field.

This study suggests that finasteride may inhibit the enzyme PNMT, potentially contributing to its sexual and psychological side effects.

This review discusses methods for improving study design and evaluation in sexual health literature and reports no new clinical results; it highlights current methodological issues and the benefits of validated questionnaires.

This study found that finasteride caused adverse effects on liver, kidney, and heart tissues in female mice, raising concerns about its potential use in females for treating androgenetic alopecia.

This study reports that a young man with severe testotoxicosis maintained spontaneous fertility despite suppressed FSH levels, underscoring the importance of high intratesticular testosterone levels for spermatogenesis.

In this study, finasteride was found not to be associated with changes in sleep spindle activity or morphology in men undergoing sleep studies.

In a rat model of benign prostatic hyperplasia, this study found that purple corn extract may improve symptoms by inhibiting prostate enlargement, reducing androgen receptor signaling, and exerting anti-inflammatory effects.

This study on rats found that finasteride and dutasteride increased collagen density in penile tissues and caused changes in prostate cells, but did not significantly alter erectile pressures compared to controls.

This article discusses the modern societal obsession with body perfection and its impact on body dissatisfaction, escalating demand for aesthetic techniques, and advertising, without reporting new research findings.

This study describes how arrector pili muscles form a single muscular structure shared by all hair follicles within a follicular unit at the isthmus level in scalp skin.

This study found that fluconazole increased water transport in renal cells via effects on aquaporin-2 channels, suggesting potential as a treatment for nephrogenic diabetes insipidus, though clinical trials are needed to confirm efficacy in humans.

In this study, fenugreek seed extract showed significant androgenic and spermatogenic effects in male rats, likely through inhibiting testosterone metabolism, without impacting cardiovascular health.

This literature review identified that phosphodiesterase 5 inhibitors, such as Tadalafil, are highly effective in improving lower urinary tract symptoms associated with benign prostatic hyperplasia, while the efficacy of saw palmetto remains inconsistent.

This study provides a comprehensive analysis of anabolic-androgenic steroids, reporting that their use enhances muscle mass but is associated with significant health issues including cardiac muscle hypertrophy, liver disease, and changes in gender characteristics, emphasizing the need for patient awareness of these risks.

This review examines the sexual side effects of 5α-reductase inhibitors like finasteride, highlighting the increased risk of erectile dysfunction, libido reduction, and potential contribution to depression without new clinical findings.

In this study, paternal exposure to finasteride prior to or during pregnancy was linked to a majority of normal full-term births, although some cases resulted in abortions, aligning with previous animal study findings.

This review covers cell transplantation methods for genitourinary reconstruction, discussing tissue sources and complications but presenting no new clinical findings.

This article discusses the increasing use of lifestyle drugs by healthy individuals to alter appearance or slow aging and emphasizes the need for doctors to consider side effects and contraindications, but it reports no new clinical findings.

The book is a detailed guide on hair and scalp diseases, useful for dermatopathologists.