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Men with severe hair loss may have a higher risk of heart disease.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Low-level laser therapy, now called photobiomodulation, is recognized for its broad medical applications and scientific backing.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

Some common medications can harm male fertility, but many effects can be reversed.

New treatments for male hypogonadism are effective and should be personalized.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

A male with aromatase deficiency improved bone health with estradiol treatment.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.