October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
January 2017 in “Clinical pharmacist” Long use of finasteride and dutasteride can cause long-term erection problems.
February 2023 in “Sexual Medicine Reviews” 1 citations,
November 2021 in “British Journal of Clinical Pharmacology”
July 2018 in “The Journal of Sexual Medicine” Gray-scale ultrasound effectively detects erectile tissue fibrosis in young men with erectile dysfunction after using finasteride.
January 2017 in “The journal of sexual medicine” Many patients with lower urinary tract symptoms also have undiagnosed erectile dysfunction, which improves with treatment.
September 2017 in “Hair transplant forum international” 2 citations,
March 2021 in “Andrologia” Stem cell therapy affects 15 key genes in rats with diabetes-related erectile dysfunction.
April 2017 in “The Journal of urology/The journal of urology” Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.
August 2008 in “The Journal of Urology” Men with urinary symptoms are more likely to have erectile dysfunction, and there's a debate about research methods and authorship ethics.
September 2018 in “Translational Andrology and Urology”
13 citations,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
April 2018 in “The Journal of Urology” Men with prediabetes have worse sexual health and a higher risk of severe erectile dysfunction.
July 2017 in “Indian journal of sexually transmitted diseases and AIDS” Finasteride, a hair loss drug, can cause sexual side effects like erectile dysfunction in 2.1%-3.8% of users, but these usually go away with time or if the drug is stopped. Despite this, its impact on sexual function is minimal for most men.
75 citations,
January 2014 in “Korean Journal of Urology” 5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
58 citations,
July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
11 citations,
January 2018 in “Asian Journal of Andrology” Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.
5 citations,
April 2016 in “PubMed” Young men with mild hair loss who experience significant social and emotional distress are more likely to have sexual problems.
May 2024 in “The journal of sexual medicine” Finasteride treatment may cause erectile dysfunction, but stopping it reverses these effects.
November 2020 in “Reactions Weekly” Finasteride can cause lasting erectile dysfunction, low libido, and depression in some patients.
May 2018 in “Reactions Weekly” Finasteride treatment for hair loss can cause erectile dysfunction.
October 2016 in “Reactions Weekly” Dutasteride and finasteride don't raise erectile dysfunction risk.
June 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride, a hair loss drug, can cause long-lasting sexual side effects like low libido and erectile dysfunction.
February 2005 in “The Journal of Urology” Finasteride for hair loss doesn't harm erectile function; weight loss and exercise improve it.
September 2019 in “Hair transplant forum international” Using finasteride may increase the risk of erectile dysfunction.
16 citations,
November 2018 in “Biochemical and Biophysical Research Communications” Sildenafil, often used for erectile dysfunction, may help hair growth.
July 2018 in “The Journal of Sexual Medicine” Low-intensity shock wave therapy is effective in treating erectile dysfunction in diabetic patients.
May 2023 in “Journal of Education, Health and Sport” Platelet-rich plasma injections can help the body heal and treat conditions like hair loss, wound healing, acne scars, erectile dysfunction, and osteoarthritis, but more research is needed.
15 citations,
January 2018 in “Acta dermato-venereologica” Finasteride and dutasteride increase sexual dysfunction risk by 1.57 times in male hair loss treatment.
June 2024 in “Georgetown medical review” Finasteride treats hair loss but may cause low libido, erectile issues, and depression.