30 citations
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December 2017 in “Medical Hypotheses” This review evaluates dihydrotestosterone's role in androgenic alopecia and proposes a model suggesting that chronic scalp tension and inflammation contribute to hair follicle miniaturization, identifying fibrosis, calcification, and tension as treatment targets.
26 citations
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May 2013 in “Marine Drugs” This study found that Ishige sinicola extract increased hair growth and cell proliferation in cultured vibrissa follicles and mice, suggesting potential benefits for treating alopecia through β-catenin activation and 5α-reductase inhibition.
25 citations
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November 2014 in “Ageing Research Reviews” This review discusses the mechanisms of skin aging, highlighting the roles of stem/progenitor cells, genetic and environmental factors, and suggests potential for cell-based therapies, but reports no new experimental findings.
25 citations
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September 2006 in “Birth Defects Research” This article discusses various skin pattern formations, their molecular mechanisms, and highlights the need for further understanding to connect molecular biology with organism phenotypes, without providing new clinical findings.
23 citations
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August 2005 in “Expert opinion on pharmacotherapy” This review examines the benefits and potential risks of androgen replacement therapy for male hypogonadism but reports no new clinical results; the authors highlight the need for careful risk assessment, especially in older men.
22 citations
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December 2016 in “PloS one” In this study, researchers found that the EDMTFH protein is present in specific layers of the chicken embryo skin and feathers, suggesting its role in feather mechanics and development.
19 citations
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January 2016 in “Biological & Pharmaceutical Bulletin” This study found that Sargassum muticum extract and apo-9′-fucoxanthinone promoted hair growth in rat and mouse models by increasing dermal papilla cell proliferation and activating certain signaling pathways.
19 citations
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August 2014 in “Journal of Ethnopharmacology” The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
19 citations
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January 2011 in “Obstetrics and gynecology international” The researchers reported that red clover extract supplementation in postmenopausal women improved subjective assessments of scalp hair, skin, libido, mood, sleep, and tiredness compared to placebo.
17 citations
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November 2012 in “Maturitas” This review discusses the management of hair loss in midlife women, focusing on female pattern hair loss, hair shaft alterations from hair care, and telogen effluvium, and reports no new research findings.
17 citations
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December 2010 in “Journal of Investigative Dermatology” This study found that higher levels of the protein Flii were associated with enhanced hair follicle regeneration and longer hair fibers in a mouse model.
15 citations
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June 2020 in “Experimental Dermatology” This review discusses recent genetic findings on hormonal signaling pathways in androgenetic alopecia, reporting no new study results but highlighting the need for further investigation.
14 citations
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July 2010 in “British Journal of Dermatology” This report discusses the possibility that estrogens might play a greater role than androgens in female pattern hair loss, without presenting new research findings.
7 citations
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June 2019 in “Australasian Journal of Dermatology” This review discusses the role of androgen hormones in the pathophysiology of childhood androgenetic alopecia and reports no clinical results.
6 citations
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April 2017 in “Journal of Dermatological Science” This study aimed to evaluate the potential use of ovariectomized mice as a model for postmenopausal female pattern hair loss, but it reports no new results.
6 citations
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January 2010 in “Springer eBooks” SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
6 citations
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November 2007 in “British Journal of Dermatology” This study found that topical fulvestrant did not significantly improve hair growth parameters in men and postmenopausal women with androgenetic alopecia, unlike minoxidil, which was more effective in men.
4 citations
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December 2013 in “British Journal of Dermatology” This study reports an association between the ESR2 gene variant rs10137185 and female-pattern hair loss in German patients.
2 citations
,
November 2013 in “Elsevier eBooks” This chapter discusses the role of hormones in regulating reproductive biology and outlines how the endocrine system, particularly the brain and pituitary gland, controls these hormonal processes.
1 citations
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September 2013 in “Elsevier eBooks” This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.
March 2024 in “International journal of pharmaceutical sciences and drug research” In this review, the authors explored current and novel treatment options for androgenetic alopecia, noting both FDA-approved pharmacologic treatments like Minoxidil and Finasteride and various non-pharmacologic and surgical methods, including hair transplantation and scalp micro-pigmentation.
June 2023 in “International journal of biology, pharmacy and allied sciences” This article discusses challenges primary care physicians face in diagnosing and treating depression, noting that up to one-third of antidepressant prescriptions involve non-indicated use; it also introduces FDA-approved treatments, esketamine nasal spray, and brexanolone IV injection.
June 2022 in “International Journal of Health Sciences (IJHS)” This review examines the role of certain proteins in the pathogenesis of polycystic ovary syndrome and reports no new results, emphasizing the potential for future diagnostic and therapeutic advancements.
May 2021 in “International journal of developmental research” This review discusses the role of sex hormones, particularly estrogen and progesterone, in melasma pathogenesis and suggests that progesterone in oral contraceptives may help prevent melasma by regulating melanocyte proliferation.
June 2018 in “International journal of trend in scientific research and development” This review discusses the formulations, mechanisms, and physiological aspects of hair cosmetics and types, but reports no new results, suggesting a foundation for future hair research.
This study characterized the physical-chemical properties of Eclipta alba and identified compounds in the plant that could support its use in developing hair loss treatments.
January 2010 in “Ciencia UANL” This study found a significant relationship between androgenetic alopecia and insulin resistance-associated indicators like obesity in young men, suggesting a potential risk for developing cardiovascular and metabolic disorders.
1 citations
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October 2022 in “Molecular therapy” This study found that betibeglogene autotemcel significantly improved transfusion independence in 89% of patients with transfusion-dependent beta-thalassemia, although the high cost and manufacturing challenges may limit widespread adoption.
September 2002 in “Oncology Times” This study presented at the ASCO Annual Meeting reported that the epidermal growth factor receptor antibody ABX-EGF showed preliminary efficacy in renal cell cancer patients, with tolerable side effects, while bortezomib demonstrated clinical benefit in a significant proportion of multiple myeloma patients.
1 citations
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September 2025 in “Frontiers in Immunology” This study found that FRβ knockout mice exhibited autoimmune symptoms and slower tumor growth compared to wild type mice, suggesting that the FRβ receptor may play a role in regulating immune responses in tumors and autoimmune conditions.