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The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.

Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

FOL-005, a hair growth promoter, acts locally on mouse skin where injected and could be a promising hair loss treatment.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

EGF controls hair growth by regulating hair follicles' growth phases.

Scalp melanoma, a deadly skin cancer, is often found late due to its hard-to-see location, especially in older men. Early detection, possible treatments, and the role of hairdressers in spotting it early are discussed. More research is needed to improve detection and treatment.

Scalp melanoma is more common and easier to diagnose early in people with androgenetic alopecia due to sun damage.

Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

Targeting colon cancer stem cells might lead to better treatment results.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Mutant mice help researchers understand hair growth and related genetic factors.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Researchers found two new genetic variants linked to Alzheimer's disease.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

EGFR inhibitors can cause various skin issues during cancer treatment, and managing these is important for patient care.